Matrixyl (200mg)

Description

Matrixyl (Palmitoyl Pentapeptide-4)

Matrixyl, also known as Palmitoyl Pentapeptide-4 or Pal-KTTKS, is a synthetic peptide that has been extensively researched for its anti-aging and skin rejuvenation properties. The peptide is designed to stimulate collagen synthesis and improve skin structure.

Chemical Makeup

Matrixyl is a lipophilic pentapeptide consisting of five amino acids (Lys-Thr-Thr-Lys-Ser) attached to a palmitic acid residue. The palmitic acid component enhances the peptide’s ability to penetrate the skin barrier, while the peptide sequence signals fibroblasts to increase collagen and other extracellular matrix protein production.

Research and Clinical Studies

Matrixyl and Collagen Stimulation

Extensive research has demonstrated Matrixyl’s ability to stimulate collagen synthesis in skin cells. In vitro studies show that Matrixyl can increase collagen type I production by up to 117%, collagen type III by 327%, and collagen type IV by 327% in cultured human fibroblasts. These dramatic increases in collagen synthesis translate to visible improvements in skin appearance.

Clinical studies have shown impressive results with topical Matrixyl application. One double-blind, placebo-controlled study demonstrated that 3% Matrixyl cream applied twice daily for 4 months resulted in a 68% average improvement in fine lines and wrinkles. Another study showed a 44% reduction in wrinkle volume and a 37% decrease in wrinkle density after 2 months of treatment.

Matrixyl and Skin Firmness

Research indicates that Matrixyl significantly improves skin firmness and elasticity. Clinical trials have shown 15-20% improvements in skin tonicity and firmness measurements after 2-4 months of use. The peptide appears to work by not only increasing collagen production but also improving the organization and quality of collagen fibers in the skin.

Studies demonstrate that Matrixyl stimulates the production of elastin, fibronectin, and glycosaminoglycans, all essential components of the extracellular matrix. This comprehensive effect on matrix components leads to improved skin structure and resilience.

Matrixyl and Wound Healing

Studies suggest that Matrixyl may accelerate wound healing and tissue repair. Research has shown that the peptide promotes fibroblast proliferation and migration, key processes in wound closure. In experimental wound models, Matrixyl treatment resulted in 25-30% faster wound closure and improved scar quality compared to controls.

Matrixyl and Photodamage Repair

Research indicates that Matrixyl may help reverse signs of photodamage (sun damage) in skin. Clinical studies have shown improvements in age spots, uneven skin tone, and sun-induced roughness with Matrixyl treatment. One study demonstrated 23% improvement in hyperpigmentation and 28% improvement in skin texture after 3 months of twice-daily application.

Matrixyl is available for research and laboratory purposes only. Please review our Terms and Conditions before placing an order.

References:

1. Robinson LR, et al. Topical palmitoyl pentapeptide provides improvement in photoaged human facial skin. Int J Cosmet Sci. 2005;27(3):155-160.
2. Katayama K, et al. A pentapeptide from type I procollagen promotes extracellular matrix production. J Biol Chem. 1993;268(14):9941-9944.